CCOI

CENTER FOR CLINICAL OBSERVATIONAL INVESTIGATIONS

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AgingResearchBiobank

MrOS: Osteoporotic Fractures in Men Study

Organization: National Institute of Aging

Description

MrOS (Osteoporotic Fractures in Men Study) is a multi-center longitudinal, observational study aimed to identify the risk factors associated with osteoporosis and bone fracture in older men (aged 65 and older). The study has been operational since 1998 and funded by National Institute on Aging (NIA), National Institute of Arthritis, Musculoskeletal, and Skin Disease (NIAMS); National Heart, Lung and Blood Institute (NHLBI) and the National Cancer Institute (NCI). In 2001, the study further expanded internationally to collaborate with sites in Hong Kong and Sweden. Study participants attended baseline examination, follow-up assessments and 5-year comprehensive assessments for physical function and performance evaluations.

Key Information

Dataset Contents
Study Date Span 2002-Present
Participant Count 5,994
Data Collection Status Ongoing
Dataset Type Medical Records, X-Ray, CT, DEXA, HRpQCT (3D) images, and Microbiome data
Region United States, Hong Kong, Sweden
Age 65 or above
Access & Availability
Native Data Structure Custom
Data Identifiability De-identified

Data Dictionary:

  • Downloadable document is available from the study homepage

Notable Publications:

Last updated Jul 16, 2025